PHRF1 promotes genome integrity by modulating non-homologous end-joining

Methylated histone readers are critical for chromatin dynamics, transcription, and DNA repair. Human PHRF1 contains a plant homeodomain (PHD) that recognizes methylated histones and a RING domain, which ubiquitinates substrates. A recent study reveals that PHRF1 is a tumor suppressor that promotes T...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cell Death Dis
Asıl Yazarlar: Chang, C-F, Chu, P-C, Wu, P-Y, Yu, M-Y, Lee, J-Y, Tsai, M-D, Chang, M-S
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2015
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650548/
https://ncbi.nlm.nih.gov/pubmed/25855964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.81
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller