Characterization of two HIV-1 infectors during initial antiretroviral treatment, and the emergence of phenotypic resistance in reverse transcriptase-associated mutation patterns

BACKGROUND: Highly active antiretroviral therapy (HAART) is recommended to control the infection of HIV-1. HIV-1 drug resistance becomes an obstacle to HAART due to the accumulation of specific mutations in the RT coding region. The development of resistance mutations may be more complex than previo...

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Dettagli Bibliografici
Pubblicato in:Virol J
Autori principali: Guo, Wei, Han, Jingwan, Zhuang, Daomin, Liu, Siyang, Liu, Yongjian, Li, Lin, Li, Hanping, Bao, Zuoyi, Wang, Fujiang, Li, Jingyun
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650308/
https://ncbi.nlm.nih.gov/pubmed/26578099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-015-0417-y
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