Impact of Y181C and/or H221Y mutation patterns of HIV-1 reverse transcriptase on phenotypic resistance to available non-nucleoside and nucleoside inhibitors in China

BACKGROUND: The aim of this study was to investigate the role of K101Q, Y181C and H221Y emerging in HIV-1 reverse transcriptase with different mutations patterns in phenotypic susceptibility to currently available NNRTIs (nevirapine NVP, efavirenz EFV) and NRTIs (zidovudine AZT, lamivudine 3TC, stav...

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Detalhes bibliográficos
Main Authors: Guo, Wei, Li, Hanping, Zhuang, Daomin, Jiao, Liyan, Liu, Siyang, Li, Lin, Liu, Yongjian, Gui, Tao, Jia, Lei, Li, Jingyun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024112/
https://ncbi.nlm.nih.gov/pubmed/24885612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-14-237
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