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Structure-based Design Targeted at LOX-1, a Receptor for Oxidized Low-Density Lipoprotein

Atherosclerosis related cardiovascular diseases continue to be the primary cause of mortality in developed countries. The elevated level of low density lipoprotein (LDL) is generally considered to be the driver of atherosclerosis, but recent years have seen a shift in this perception in that the vas...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Thakkar, Shraddha, Wang, Xianwei, Khaidakov, Magomed, Dai, Yao, Gokulan, Kuppan, Mehta, Jawahar L., Varughese, Kottayil I.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649741/
https://ncbi.nlm.nih.gov/pubmed/26578342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16740
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