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Structure-based Design Targeted at LOX-1, a Receptor for Oxidized Low-Density Lipoprotein

Atherosclerosis related cardiovascular diseases continue to be the primary cause of mortality in developed countries. The elevated level of low density lipoprotein (LDL) is generally considered to be the driver of atherosclerosis, but recent years have seen a shift in this perception in that the vas...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Thakkar, Shraddha, Wang, Xianwei, Khaidakov, Magomed, Dai, Yao, Gokulan, Kuppan, Mehta, Jawahar L., Varughese, Kottayil I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649741/
https://ncbi.nlm.nih.gov/pubmed/26578342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16740
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