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Structure-based Design Targeted at LOX-1, a Receptor for Oxidized Low-Density Lipoprotein

Atherosclerosis related cardiovascular diseases continue to be the primary cause of mortality in developed countries. The elevated level of low density lipoprotein (LDL) is generally considered to be the driver of atherosclerosis, but recent years have seen a shift in this perception in that the vas...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Thakkar, Shraddha, Wang, Xianwei, Khaidakov, Magomed, Dai, Yao, Gokulan, Kuppan, Mehta, Jawahar L., Varughese, Kottayil I.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649741/
https://ncbi.nlm.nih.gov/pubmed/26578342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16740
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