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Phase I and pharmacological trial of lapatinib in combination with gemcitabine in patients with advanced breast cancer
Background Lapatinib has proven efficacy as monotherapy and in combination with capecitabine in patients with metastatic breast cancer (MBC) overexpressing HER2 and/or EGFR. Gemcitabine also has anti-tumor activity in MBC and a favourable toxicity profile. In this phase I study lapatinib and gemcita...
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| Vydáno v: | Invest New Drugs |
|---|---|
| Hlavní autoři: | , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Springer US
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4648969/ https://ncbi.nlm.nih.gov/pubmed/26362459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-015-0281-z |
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