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Lapatinib for Advanced or Metastatic Breast Cancer
Lapatinib is a potent reversible and selective inhibitor of the tyrosine kinase domains of epidermal growth factor receptor and human epidermal growth factor receptor (HER)-2 that exerts its action by competitive binding to the intracellular ATP-binding site of the receptor. It is registered for the...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
AlphaMed Press
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3336826/ https://ncbi.nlm.nih.gov/pubmed/22477724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2011-0461 |
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