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Antidrug Antibody Formation in Oncology: Clinical Relevance and Challenges

In oncology, an increasing number of targeted anticancer agents and immunotherapies are of biological origin. These biological drugs may trigger immune responses that lead to the formation of antidrug antibodies (ADAs). ADAs are directed against immunogenic parts of the drug and may affect efficacy...

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Dades bibliogràfiques
Publicat a:Oncologist
Autors principals: van Brummelen, Emilie M.J., Ros, Willeke, Wolbink, Gertjan, Beijnen, Jos H., Schellens, Jan H.M.
Format: Artigo
Idioma:Inglês
Publicat: AlphaMed Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5061540/
https://ncbi.nlm.nih.gov/pubmed/27440064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2016-0061
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