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Antidrug Antibody Formation in Oncology: Clinical Relevance and Challenges

In oncology, an increasing number of targeted anticancer agents and immunotherapies are of biological origin. These biological drugs may trigger immune responses that lead to the formation of antidrug antibodies (ADAs). ADAs are directed against immunogenic parts of the drug and may affect efficacy...

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Bibliografski detalji
Izdano u:Oncologist
Glavni autori: van Brummelen, Emilie M.J., Ros, Willeke, Wolbink, Gertjan, Beijnen, Jos H., Schellens, Jan H.M.
Format: Artigo
Jezik:Inglês
Izdano: AlphaMed Press 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5061540/
https://ncbi.nlm.nih.gov/pubmed/27440064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2016-0061
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