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Antidrug Antibody Formation in Oncology: Clinical Relevance and Challenges

In oncology, an increasing number of targeted anticancer agents and immunotherapies are of biological origin. These biological drugs may trigger immune responses that lead to the formation of antidrug antibodies (ADAs). ADAs are directed against immunogenic parts of the drug and may affect efficacy...

詳細記述

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書誌詳細
出版年:Oncologist
主要な著者: van Brummelen, Emilie M.J., Ros, Willeke, Wolbink, Gertjan, Beijnen, Jos H., Schellens, Jan H.M.
フォーマット: Artigo
言語:Inglês
出版事項: AlphaMed Press 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5061540/
https://ncbi.nlm.nih.gov/pubmed/27440064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2016-0061
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