Lapatinib for Advanced or Metastatic Breast Cancer

Lapatinib is a potent reversible and selective inhibitor of the tyrosine kinase domains of epidermal growth factor receptor and human epidermal growth factor receptor (HER)-2 that exerts its action by competitive binding to the intracellular ATP-binding site of the receptor. It is registered for the...

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Bibliografiske detaljer
Main Authors: Opdam, Frans L., Guchelaar, Henk-Jan, Beijnen, Jos H., Schellens, Jan H.M.
Format: Artigo
Sprog:Inglês
Udgivet: AlphaMed Press 2012
Fag:
New Drug Development and Clinical Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336826/
https://ncbi.nlm.nih.gov/pubmed/22477724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2011-0461
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