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BRG1 Governs Nanog Transcription in Early Mouse Embryos and Embryonic Stem Cells via Antagonism of Histone H3 Lysine 9/14 Acetylation

During mouse preimplantation development, the generation of the inner cell mass (ICM) and trophoblast lineages comprises upregulation of Nanog expression in the ICM and its silencing in the trophoblast. However, the underlying epigenetic mechanisms that differentially regulate Nanog in the first cel...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Carey, Timothy S., Cao, Zubing, Choi, Inchul, Ganguly, Avishek, Wilson, Catherine A., Paul, Soumen, Knott, Jason G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648823/
https://ncbi.nlm.nih.gov/pubmed/26416882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00546-15
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