Transcription factor AP-2γ induces early Cdx2 expression and represses HIPPO signaling to specify the trophectoderm lineage

Cell fate decisions are fundamental to the development of multicellular organisms. In mammals the first cell fate decision involves segregation of the pluripotent inner cell mass and the trophectoderm, a process regulated by cell polarity proteins, HIPPO signaling and lineage-specific transcription...

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Publicado en:Development
Autores principales: Cao, Zubing, Carey, Timothy S., Ganguly, Avishek, Wilson, Catherine A., Paul, Soumen, Knott, Jason G.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Company of Biologists 2015
Materias:
Stem Cells and Regeneration
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4419278/
https://ncbi.nlm.nih.gov/pubmed/25858457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.120238
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