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Mapping Dynamic Histone Acetylation Patterns to Gene Expression in Nanog-Depleted Murine Embryonic Stem Cells

Embryonic stem cells (ESC) have the potential to self-renew indefinitely and to differentiate into any of the three germ layers. The molecular mechanisms for self-renewal, maintenance of pluripotency and lineage specification are poorly understood, but recent results point to a key role for epigenet...

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Hlavní autoři: Markowetz, Florian, Mulder, Klaas W., Airoldi, Edoardo M., Lemischka, Ihor R., Troyanskaya, Olga G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002996/
https://ncbi.nlm.nih.gov/pubmed/21187909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1001034
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