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The Grb2/Mek Pathway Represses Nanog in Murine Embryonic Stem Cells
The homeobox gene Nanog is a key intrinsic determinant of self renewal in embryonic stem (ES) cells, and its repression leads ES cells to selectively differentiate into primitive endoderm. Although Nanog repression occurs at the outermost layer of ES cell aggregates independent of the leukemia inhib...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1636849/ https://ncbi.nlm.nih.gov/pubmed/16908534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00508-06 |
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