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Activation of the amino acid response modulates lineage specification during differentiation of murine embryonic stem cells

In somatic cells, a collection of signaling pathways activated by amino acid limitation have been identified and referred to as the amino acid response (AAR). Despite the importance of possible detrimental effects of nutrient limitation during in vitro culture, the AAR has not been investigated in e...

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Detalhes bibliográficos
Main Authors: Shan, Jixiu, Hamazaki, Takashi, Tang, Tiffany A., Terada, Naohiro, Kilberg, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116408/
https://ncbi.nlm.nih.gov/pubmed/23736538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00136.2013
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