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Microenvironment Modulates Osteogenic Cell Lineage Commitment in Differentiated Embryonic Stem Cells

BACKGROUND: Due to their self-renewal, embryonic stem cells (ESCs) are attractive cells for applications in regenerative medicine and tissue engineering. Although ESC differentiation has been used as a platform for generating bone in vitro and in vivo, the results have been unsatisfactory at best. I...

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Main Authors: Yamashita, Akihiro, Nishikawa, Sandi, Rancourt, Derrick E.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837348/
https://ncbi.nlm.nih.gov/pubmed/20300192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009663
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