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Coupling Binding to Catalysis – Using Yeast Cell Surface Display to Select Enzymatic Activities

We find yeast cell surface display can be used to engineer enzymes by selecting the enzyme library for high affinity binding to reaction intermediates. Here we cover key steps of enzyme engineering on the yeast cell surface including library design, construction, and selection based on magnetic and...

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Vydáno v:Methods Mol Biol
Hlavní autoři: Zhang, Keya, Bhuripanyo, Karan, Wang, Yiyang, Yin, Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648535/
https://ncbi.nlm.nih.gov/pubmed/26060080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-2748-7_14
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