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Coupling Binding to Catalysis – Using Yeast Cell Surface Display to Select Enzymatic Activities

We find yeast cell surface display can be used to engineer enzymes by selecting the enzyme library for high affinity binding to reaction intermediates. Here we cover key steps of enzyme engineering on the yeast cell surface including library design, construction, and selection based on magnetic and...

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Détails bibliographiques
Publié dans:Methods Mol Biol
Auteurs principaux: Zhang, Keya, Bhuripanyo, Karan, Wang, Yiyang, Yin, Jun
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648535/
https://ncbi.nlm.nih.gov/pubmed/26060080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-2748-7_14
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