MBSTAR: multiple instance learning for predicting specific functional binding sites in microRNA targets

MicroRNA (miRNA) regulates gene expression by binding to specific sites in the 3′untranslated regions of its target genes. Machine learning based miRNA target prediction algorithms first extract a set of features from potential binding sites (PBSs) in the mRNA and then train a classifier to distingu...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Bandyopadhyay, Sanghamitra, Ghosh, Dip, Mitra, Ramkrishna, Zhao, Zhongming
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648438/
https://ncbi.nlm.nih.gov/pubmed/25614300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08004
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