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A Tri-Component Conservation Strategy Reveals Highly Confident MicroRNA-mRNA Interactions and Evolution of MicroRNA Regulatory Networks

MicroRNAs are small non-coding RNAs that can regulate expressions of their target genes at the post-transcriptional level. In this study, we propose a tri-component strategy that combines the conservation of microRNAs, homology of mRNA coding regions, and conserved microRNA binding sites in the 3′ u...

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Bibliografske podrobnosti
Main Authors: Lin, Chen-Ching, Mitra, Ramkrishna, Zhao, Zhongming
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4108425/
https://ncbi.nlm.nih.gov/pubmed/25054916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103142
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