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MBSTAR: multiple instance learning for predicting specific functional binding sites in microRNA targets

MicroRNA (miRNA) regulates gene expression by binding to specific sites in the 3′untranslated regions of its target genes. Machine learning based miRNA target prediction algorithms first extract a set of features from potential binding sites (PBSs) in the mRNA and then train a classifier to distingu...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Bandyopadhyay, Sanghamitra, Ghosh, Dip, Mitra, Ramkrishna, Zhao, Zhongming
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648438/
https://ncbi.nlm.nih.gov/pubmed/25614300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08004
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