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MBSTAR: multiple instance learning for predicting specific functional binding sites in microRNA targets

MicroRNA (miRNA) regulates gene expression by binding to specific sites in the 3′untranslated regions of its target genes. Machine learning based miRNA target prediction algorithms first extract a set of features from potential binding sites (PBSs) in the mRNA and then train a classifier to distingu...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Bandyopadhyay, Sanghamitra, Ghosh, Dip, Mitra, Ramkrishna, Zhao, Zhongming
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648438/
https://ncbi.nlm.nih.gov/pubmed/25614300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08004
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