Concordant dysregulation of miR-5p and miR-3p arms of the same precursor microRNA may be a mechanism in inducing cell proliferation and tumorigenesis: a lung cancer study

A precursor microRNA (miRNA) has two arms: miR-5p and miR-3p (miR-5p/-3p). Depending on the tissue or cell types, both arms can become functional. However, little is known about their coregulatory mechanisms during the tumorigenic process. Here, by using the large-scale miRNA expression profiles of...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Mitra, Ramkrishna, Lin, Chen-Ching, Eischen, Christine M., Bandyopadhyay, Sanghamitra, Zhao, Zhongming
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2015
Assuntos:
Bioinformatics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4436660/
https://ncbi.nlm.nih.gov/pubmed/25852169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.048132.114
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