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MultiMiTar: A Novel Multi Objective Optimization based miRNA-Target Prediction Method

BACKGROUND: Machine learning based miRNA-target prediction algorithms often fail to obtain a balanced prediction accuracy in terms of both sensitivity and specificity due to lack of the gold standard of negative examples, miRNA-targeting site context specific relevant features and efficient feature...

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Detalhes bibliográficos
Main Authors: Mitra, Ramkrishna, Bandyopadhyay, Sanghamitra
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174180/
https://ncbi.nlm.nih.gov/pubmed/21949731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024583
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