A carregar...

Optimizing Synthetic miRNA Minigene Architecture for Efficient miRNA Hairpin Concatenation and Multi-target Gene Knockdown

Synthetic microRNA (miRNA) minigenes (SMIGs) have a major potential for molecular therapy; however, their optimal architecture still needs to be determined. We have previously optimized the stem structure of miRNA hairpins for efficient gene knockdown. Here, we investigate the overall architecture o...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Rousset, Francis, Salmon, Patrick, Bredl, Simon, Cherpin, Ophélie, Coelho, Marta, Myburgh, Renier, Alessandrini, Marco, Perny, Michael, Roccio, Marta, Speck, Roberto F., Senn, Pascal, Krause, Karl Heinz
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6350225/
https://ncbi.nlm.nih.gov/pubmed/30665184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.12.004
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!