Ribosome biogenesis dysfunction leads to p53-mediated apoptosis and goblet cell differentiation of mouse intestinal stem/progenitor cells

Ribosome biogenesis is an essential cellular process. Its impairment is associated with developmental defects and increased risk of cancer. The in vivo cellular responses to defective ribosome biogenesis and the underlying molecular mechanisms are still incompletely understood. In particular, the co...

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Publicado en:Cell Death Differ
Autores principales: Stedman, A, Beck-Cormier, S, Le Bouteiller, M, Raveux, A, Vandormael-Pournin, S, Coqueran, S, Lejour, V, Jarzebowski, L, Toledo, F, Robine, S, Cohen-Tannoudji, M
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2015
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Original Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648334/
https://ncbi.nlm.nih.gov/pubmed/26068591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.57
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