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Age-associated inflammation connects RAS-induced senescence to stem cell dysfunction and epidermal malignancy
Aging is the single biggest risk factor for malignant transformation. Among the most common age-associated malignancies are non-melanoma skin cancers, comprising the most common types of human cancer. Here we show that mutant H-Ras activation in mouse epidermis, a frequent event in cutaneous squamou...
שמור ב:
| הוצא לאור ב: | Cell Death Differ |
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| Main Authors: | , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4648323/ https://ncbi.nlm.nih.gov/pubmed/26434982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.21 |
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