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Granule exocytosis mediates immune surveillance of senescent cells

Senescence is a stable cell cycle arrest program that contributes to tumor suppression, organismal aging and certain wound healing responses. During liver fibrosis, for example, hepatic stellate cells initially proliferate and secrete extracellular matrix components that produce fibrosis; however, t...

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Autors principals: Sagiv, A, Biran, A, Yon, M, Simon, J, Lowe, S W, Krizhanovsky, V
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630483/
https://ncbi.nlm.nih.gov/pubmed/22751116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.206
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