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Granule exocytosis mediates immune surveillance of senescent cells

Senescence is a stable cell cycle arrest program that contributes to tumor suppression, organismal aging and certain wound healing responses. During liver fibrosis, for example, hepatic stellate cells initially proliferate and secrete extracellular matrix components that produce fibrosis; however, t...

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Hlavní autoři: Sagiv, A, Biran, A, Yon, M, Simon, J, Lowe, S W, Krizhanovsky, V
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630483/
https://ncbi.nlm.nih.gov/pubmed/22751116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.206
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