Expression profiles of 151 pediatric low-grade gliomas reveal molecular differences associated with location and histological subtype

BACKGROUND: Pediatric low-grade gliomas (PLGGs), the most frequent pediatric brain tumor, comprise a heterogeneous group of diseases. Recent genomic analyses suggest that these tumors are mostly driven by mitogene-activated protein kinase (MAPK) pathway alterations. However, little is known about th...

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發表在:Neuro Oncol
Main Authors: Bergthold, Guillaume, Bandopadhayay, Pratiti, Hoshida, Yujin, Ramkissoon, Shakti, Ramkissoon, Lori, Rich, Benjamin, Maire, Cecile L., Paolella, Brenton R., Schumacher, Steven E., Tabak, Barbara, Ferrer-Luna, Ruben, Ozek, Memet, Sav, Aydin, Santagata, Sandro, Wen, Patrick Yung, Goumnerova, Liliana C., Ligon, Azra H., Stiles, Charles, Segal, Rosalind, Golub, Todd, Grill, Jacques, Ligon, Keith L., Chan, Jennifer A., Kieran, Mark W., Beroukhim, Rameen
格式: Artigo
語言:Inglês
出版: Oxford University Press 2015
主題:
Basic and Translational Investigations
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648300/
https://ncbi.nlm.nih.gov/pubmed/25825052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov045
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