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A model of a patient-derived IDH1 mutant anaplastic astrocytoma with alternative lengthening of telomeres
Mutations in isocitrate dehydrogenase 1 (IDH1) have been found in the vast majority of low grade and progressive infiltrating gliomas and are characterized by the production of 2-hydroxyglutarate from α-ketoglutarate. Recent investigations of malignant gliomas have identified additional genetic and...
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| Publicado no: | J Neurooncol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4648276/ https://ncbi.nlm.nih.gov/pubmed/25471051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-014-1672-2 |
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