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A model of a patient-derived IDH1 mutant anaplastic astrocytoma with alternative lengthening of telomeres

Mutations in isocitrate dehydrogenase 1 (IDH1) have been found in the vast majority of low grade and progressive infiltrating gliomas and are characterized by the production of 2-hydroxyglutarate from α-ketoglutarate. Recent investigations of malignant gliomas have identified additional genetic and...

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Foilsithe in:J Neurooncol
Main Authors: Borodovsky, Alexandra, Meeker, Alan K., Kirkness, Ewen F., Zhao, Qi, Eberhart, Charles G., Gallia, Gary L., Riggins, Gregory J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648276/
https://ncbi.nlm.nih.gov/pubmed/25471051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-014-1672-2
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