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Potent and Selective Modulation of the RhlR Quorum Sensing Receptor using Non-Native Ligands – An Emerging Target for Virulence Control in Pseudomonas aeruginosa
Pseudomonas aeruginosa uses N-acylated L-homoserine lactone signals and a triumvirate of LuxR-type receptor proteins – LasR, RhlR, and QscR – for quorum sensing (QS). Each of these receptors can contribute to QS activation or repression, and thereby, the control of myriad virulence phenotypes in thi...
Shranjeno v:
izdano v: | Chembiochem |
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Main Authors: | , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
2015
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4648260/ https://ncbi.nlm.nih.gov/pubmed/26460240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201500357 |
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