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Cytotoxic granule secretion by lymphocytes and its link to immune homeostasis

The granule-dependent cytotoxic activity of T and natural killer lymphocytes has progressively emerged as an important effector pathway not only for host defence but also for immune regulation. The analysis of an early-onset, severe, primary immune dysregulatory syndrome known as hemophagocytic lymp...

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Pubblicato in:F1000Res
Autori principali: de Saint Basile, Geneviève, Sepulveda, Fernando E., Maschalidi, Sophia, Fischer, Alain
Natura: Artigo
Lingua:Inglês
Pubblicazione: F1000Research 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648190/
https://ncbi.nlm.nih.gov/pubmed/26594351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.6754.1
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