טוען...
Mutation of the TERT promoter, switch to active chromatin, and monoallelic TERT expression in multiple cancers
Somatic mutations in the promoter of the gene for telomerase reverse transcriptase (TERT) are the most common noncoding mutations in cancer. They are thought to activate telomerase, contributing to proliferative immortality, but the molecular events driving TERT activation are largely unknown. We ob...
שמור ב:
| הוצא לאור ב: | Genes Dev |
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| Main Authors: | , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Cold Spring Harbor Laboratory Press
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4647555/ https://ncbi.nlm.nih.gov/pubmed/26515115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.269498.115 |
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