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A Medium-Throughput Single Cell CRISPR-Cas9 Assay to Assess Gene Essentiality
BACKGROUND: Target selection for oncology is a crucial step in the successful development of therapeutics. Clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 editing of specific loci offers an alternative method to RNA interference and small molecule inhibitors for determining w...
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Publicado no: | Biol Proced Online |
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Main Authors: | , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4647477/ https://ncbi.nlm.nih.gov/pubmed/26578851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12575-015-0028-4 |
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