IL-6 signaling promotes DNA repair and prevents apoptosis in CD133+ stem-like cells of lung cancer after radiation

BACKGROUND: Local tumor control by standard fractionated radiotherapy (RT) remains poor because of tumor resistance to radiation (radioresistance). It has been suggested that cancer stem cells (CSCs) are more radioresistant than non-CSCs. In previous studies, we have shown IL-6 promotes self-renewal...

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Detalles Bibliográficos
Publicado en:Radiat Oncol
Main Authors: Chen, Yuhchyau, Zhang, Fuquan, Tsai, Ying, Yang, Xiadong, Yang, Li, Duan, Shanzhou, Wang, Xin, Keng, Peter, Lee, Soo Ok
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2015
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647293/
https://ncbi.nlm.nih.gov/pubmed/26572130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13014-015-0534-1
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