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Cisplatin treatment increases stemness through upregulation of hypoxia‐inducible factors by interleukin‐6 in non‐small cell lung cancer

Cisplatin‐resistant A549 and H157 (A549CisR and H157CisR) non‐small cell lung cancer cells show increased stemness of cancer stem cells (CSCs) compared to their parental cells. We investigated whether interleukin‐6 (IL‐6) signaling contributes to this increased stemness in cisplatin‐resistant cells....

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Zhang, Fuquan, Duan, Shanzhou, Tsai, Ying, Keng, Peter C., Chen, Yongbing, Lee, Soo Ok, Chen, Yuhchyau
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968604/
https://ncbi.nlm.nih.gov/pubmed/27009878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12937
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