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Cisplatin treatment increases stemness through upregulation of hypoxia‐inducible factors by interleukin‐6 in non‐small cell lung cancer

Cisplatin‐resistant A549 and H157 (A549CisR and H157CisR) non‐small cell lung cancer cells show increased stemness of cancer stem cells (CSCs) compared to their parental cells. We investigated whether interleukin‐6 (IL‐6) signaling contributes to this increased stemness in cisplatin‐resistant cells....

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Détails bibliographiques
Publié dans:Cancer Sci
Auteurs principaux: Zhang, Fuquan, Duan, Shanzhou, Tsai, Ying, Keng, Peter C., Chen, Yongbing, Lee, Soo Ok, Chen, Yuhchyau
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968604/
https://ncbi.nlm.nih.gov/pubmed/27009878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12937
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