Abnormal Protein Glycosylation and Activated PI3K/Akt/mTOR Pathway: Role in Bladder Cancer Prognosis and Targeted Therapeutics

Muscle invasive bladder cancer (MIBC, stage ≥T2) is generally associated with poor prognosis, constituting the second most common cause of death among genitourinary tumours. Due to high molecular heterogeneity significant variations in the natural history and disease outcome have been observed. This...

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Vydáno v:PLoS One
Hlavní autoři: Costa, Céu, Pereira, Sofia, Lima, Luís, Peixoto, Andreia, Fernandes, Elisabete, Neves, Diogo, Neves, Manuel, Gaiteiro, Cristiana, Tavares, Ana, Gil da Costa, Rui M., Cruz, Ricardo, Amaro, Teresina, Oliveira, Paula A., Ferreira, José Alexandre, Santos, Lúcio L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646664/
https://ncbi.nlm.nih.gov/pubmed/26569621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141253
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