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Abnormal Protein Glycosylation and Activated PI3K/Akt/mTOR Pathway: Role in Bladder Cancer Prognosis and Targeted Therapeutics

Muscle invasive bladder cancer (MIBC, stage ≥T2) is generally associated with poor prognosis, constituting the second most common cause of death among genitourinary tumours. Due to high molecular heterogeneity significant variations in the natural history and disease outcome have been observed. This...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Costa, Céu, Pereira, Sofia, Lima, Luís, Peixoto, Andreia, Fernandes, Elisabete, Neves, Diogo, Neves, Manuel, Gaiteiro, Cristiana, Tavares, Ana, Gil da Costa, Rui M., Cruz, Ricardo, Amaro, Teresina, Oliveira, Paula A., Ferreira, José Alexandre, Santos, Lúcio L.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646664/
https://ncbi.nlm.nih.gov/pubmed/26569621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141253
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