Hypoxia enhances the malignant nature of bladder cancer cells and concomitantly antagonizes protein O-glycosylation extension

Invasive bladder tumours express the cell-surface Sialyl-Tn (STn) antigen, which stems from a premature stop in protein O-glycosylation. The STn antigen favours invasion, immune escape, and possibly chemotherapy resistance, making it attractive for target therapeutics. However, the events leading to...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Peixoto, Andreia, Fernandes, Elisabete, Gaiteiro, Cristiana, Lima, Luís, Azevedo, Rita, Soares, Janine, Cotton, Sofia, Parreira, Beatriz, Neves, Manuel, Amaro, Teresina, Tavares, Ana, Teixeira, Filipe, Palmeira, Carlos, Rangel, Maria, Silva, André M.N., Reis, Celso A., Santos, Lúcio Lara, Oliveira, Maria José, Ferreira, José Alexandre
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325352/
https://ncbi.nlm.nih.gov/pubmed/27542232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11257
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