Head-to-Head Comparison of Soluble vs. Qβ VLP Circumsporozoite Protein Vaccines Reveals Selective Enhancement of NANP Repeat Responses

Circumsporozoite protein (CSP) of Plasmodium falciparum is a promising malaria vaccine target. RTS,S, the most advanced malaria vaccine candidate consists of the central NANP repeat and carboxy-terminal region of CSP displayed on a hepatitis B virus-like particle (VLP). To build upon the success of...

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Bibliographic Details
Published in:PLoS One
Main Authors: Khan, Farhat, Porter, Mike, Schwenk, Robert, DeBot, Margot, Saudan, Philippe, Dutta, Sheetij
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646581/
https://ncbi.nlm.nih.gov/pubmed/26571021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142035
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