IgG2 Antibodies against a Clinical Grade Plasmodium falciparum CSP Vaccine Antigen Associate with Protection against Transgenic Sporozoite Challenge in Mice

The availability of a highly purified and well characterized circumsporozoite protein (CSP) is essential to improve upon the partial success of recombinant CSP-based malaria vaccine candidates. Soluble, near full-length, Plasmodium falciparum CSP vaccine antigen (CS/D) was produced in E. coli under...

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Detalhes bibliográficos
Main Authors: Schwenk, Robert, DeBot, Margot, Porter, Michael, Nikki, Jennifer, Rein, Lisa, Spaccapelo, Roberta, Crisanti, Andrea, Wightman, Paul D., Ockenhouse, Christian F., Dutta, Sheetij
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208815/
https://ncbi.nlm.nih.gov/pubmed/25343487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111020
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