Comparative population structure of Plasmodium falciparum circumsporozoite protein NANP repeat lengths in Lilongwe, Malawi

Humoral immunity to Plasmodium falciparum circumsporozoite protein is partly mediated by a polymorphic NANP tetra-amino acid repeat. Antibody response to these repeats is the best correlate of protective immunity to the RTS,S malaria vaccine, but few descriptions of the natural variation of these re...

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Detalhes bibliográficos
Main Authors: Bowman, Natalie M., Congdon, Seth, Mvalo, Tisungane, Patel, Jaymin C., Escamilla, Veronica, Emch, Michael, Martinson, Francis, Hoffman, Irving, Meshnick, Steven R., Juliano, Jonathan J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683670/
https://ncbi.nlm.nih.gov/pubmed/23771124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01990
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