A Natural Product from Polygonum cuspidatum Sieb. Et Zucc. Promotes Tat-Dependent HIV Latency Reversal through Triggering P-TEFb’s Release from 7SK snRNP

The latent reservoirs of HIV represent a major impediment to eradication of HIV/AIDS. To overcome this problem, agents that can activate latent HIV proviruses have been actively sought after, as they can potentially be used in combination with the highly active antiretroviral therapy (HAART) to elim...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wang, Cong, Yang, Shuiyuan, Lu, Huasong, You, Hongchao, Ni, Man, Shan, Wenjun, Lin, Ting, Gao, Xiang, Chen, Haifeng, Zhou, Qiang, Xue, Yuhua
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646521/
https://ncbi.nlm.nih.gov/pubmed/26569506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142739
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