Antioncogenic and Oncogenic Properties of Nrf2 in Arsenic-induced Carcinogenesis

Arsenic (As(3+)) is a carcinogen with considerable environmental and occupational relevancy. The present study shows that As(3+)-transformed human lung bronchial epithelial BEAS-2B cells (AsT cells) exhibit the property of apoptosis resistance. The level of basal reactive oxygen species (ROS) is ver...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Son, Young-Ok, Pratheeshkumar, Poyil, Roy, Ram Vinod, Hitron, John Andrew, Wang, Lei, Divya, Sasidharan Padmaja, Xu, Mei, Luo, Jia, Chen, Gang, Zhang, Zhuo, Shi, Xianglin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646382/
https://ncbi.nlm.nih.gov/pubmed/26385919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.675371
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