Different roles of ROS and Nrf2 in Cr(VI)-induced inflammatory responses in normal and Cr(VI)-transformed cells

Hexavalent chromium (Cr(VI)) is classified as a human carcinogen. Cr(VI) has been associated with adenocarcinomas and squamous cell carcinoma of the lung. The present study shows that acute Cr(VI) treatment in human bronchial epithelial cells (BEAS-2B) increased inflammatory responses (TNF-α, COX-2,...

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Veröffentlicht in:Toxicol Appl Pharmacol
Hauptverfasser: Roy, Ram Vinod, Pratheeshkumar, Poyil, Son, Yong-Ok, Wang, Lei, Hitron, John Andrew, Divya, Sasidharan Padmaja, Zhang, Zhuo, Shi, Xianglin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527995/
https://ncbi.nlm.nih.gov/pubmed/27470422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2016.07.016
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