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Nrf2/p62 Signaling in Apoptosis Resistance and Its Role in Cadmium-induced Carcinogenesis

The cadmium-transformed human lung bronchial epithelial BEAS-2B cells exhibit a property of apoptosis resistance as compared with normal non-transformed BEAS-2B cells. The level of basal reactive oxygen species (ROS) is extremely low in transformed cells in correlation with elevated expressions of b...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Son, Young-Ok, Pratheeshkumar, Poyil, Roy, Ram Vinod, Hitron, John Andrew, Wang, Lei, Zhang, Zhuo, Shi, Xianglin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192515/
https://ncbi.nlm.nih.gov/pubmed/25157103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.595496
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