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Specific Chaperones and Regulatory Domains in Control of Amyloid Formation

Many proteins can form amyloid-like fibrils in vitro, but only about 30 amyloids are linked to disease, whereas some proteins form physiological amyloid-like assemblies. This raises questions of how the formation of toxic protein species during amyloidogenesis is prevented or contained in vivo. Intr...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Landreh, Michael, Rising, Anna, Presto, Jenny, Jörnvall, Hans, Johansson, Jan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646301/
https://ncbi.nlm.nih.gov/pubmed/26354437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R115.653097
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