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Unique Role of the WD-40 Repeat Protein 5 (WDR5) Subunit within the Mixed Lineage Leukemia 3 (MLL3) Histone Methyltransferase Complex

The MLL3 (mixed lineage leukemia 3) protein is a member of the human SET1 family of histone H3 lysine 4 methyltransferases and contains the conserved WDR5 interaction (Win) motif and the catalytic suppressor of variegation, enhancer of zeste, trithorax (SET) domain. The human SET1 family includes ML...

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Foilsithe in:J Biol Chem
Main Authors: Shinsky, Stephen A., Cosgrove, Michael S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646236/
https://ncbi.nlm.nih.gov/pubmed/26324722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.684142
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