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2-DG-Regulated RIP and c-FLIP Effect on Liver Cancer Cell Apoptosis Induced by TRAIL

BACKGROUND: Cancer cells survival depends on glucose metabolism and ATP. Inhibiting glucose metabolism is a possible anticancer treatment. The phosphorylation of 2-deoxy-D-glucose (2-DG), which is a glycogen analogue, seriously affects the normal glycometabolism phosphorylation process, leading to A...

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Detalhes bibliográficos
Publicado no:Med Sci Monit
Principais autores: Zhang, Yuping, Huang, Feizhou, Wang, Jian, Luo, Hongwu, Wang, Zhichao
Formato: Artigo
Idioma:Inglês
Publicado em: International Scientific Literature, Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646230/
https://ncbi.nlm.nih.gov/pubmed/26552967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.895034
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