Brain-expressed X-linked 2 Is Pivotal for Hyperactive Mechanistic Target of Rapamycin (mTOR)-mediated Tumorigenesis

Frequent alteration of upstream proto-oncogenes and tumor suppressor genes activates mechanistic target of rapamycin (mTOR) and causes cancer. However, the downstream effectors of mTOR remain largely elusive. Here we report that brain-expressed X-linked 2 (BEX2) is a novel downstream effector of mTO...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Hu, Zhongdong, Wang, Ying, Huang, Fuqiang, Chen, Rongrong, Li, Chunjia, Wang, Fang, Goto, June, Kwiatkowski, David J., Wdzieczak-Bakala, Joanna, Tu, Pengfei, Liu, Jianmiao, Zha, Xiaojun, Zhang, Hongbing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646217/
https://ncbi.nlm.nih.gov/pubmed/26296882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.665208
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados