Identification and Small Molecule Inhibition of an Activating Transcription Factor 4 (ATF4)-dependent Pathway to Age-related Skeletal Muscle Weakness and Atrophy

Aging reduces skeletal muscle mass and strength, but the underlying molecular mechanisms remain elusive. Here, we used mouse models to investigate molecular mechanisms of age-related skeletal muscle weakness and atrophy as well as new potential interventions for these conditions. We identified two s...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Ebert, Scott M., Dyle, Michael C., Bullard, Steven A., Dierdorff, Jason M., Murry, Daryl J., Fox, Daniel K., Bongers, Kale S., Lira, Vitor A., Meyerholz, David K., Talley, John J., Adams, Christopher M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2015
Konular:
Molecular Bases of Disease
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646196/
https://ncbi.nlm.nih.gov/pubmed/26338703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.681445
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller